165 Results for "

Morus nigra Linn.

" in MedChemExpress (MCE) Product Catalog:
Products (165)

165 Results for "Morus nigra Linn." in MCE Product Catalog:

53
53 Publications Verification
製品番号: HY-13251
CAS 番号: 697235-38-4
純度:  99.96%
別名: (-)-Silvestrol
Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
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37
37 Cited Publications
製品番号: HY-W008719
CAS 番号: 36913-39-0
研究分野:  

Neurological Disease

MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT) .
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29
29 Cited Publications
製品番号: HY-B0451
CAS 番号: 51-61-6
別名: ASL279 free base
Dopamine is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine plays several important roles in the brain and body . Dopamine acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis .
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29
29 Cited Publications
製品番号: HY-B0451A
CAS 番号: 62-31-7
別名: ASL279
Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body . Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis .
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14
14 Cited Publications
製品番号: HY-N0622
CAS 番号: 62596-29-6
別名: Mulberrochromene
Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.
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14
14 Cited Publications
製品番号: HY-N0013
CAS 番号: 3681-93-4
Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
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11
11 Cited Publications
製品番号: HY-N0116
CAS 番号: 517-28-2
別名: Natural Black 1; Haematoxylin
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
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10
10 Cited Publications
製品番号: HY-13065
CAS 番号: 20784-50-3
純度:  99.01%
別名: Corylifolinin; Isobacachalcone
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
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4
4 Cited Publications
製品番号: HY-50730
CAS 番号: 2224-02-4
Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .
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4
4 Cited Publications
製品番号: HY-N0619
CAS 番号: 102841-42-9
Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.) . Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects . Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM .
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3
3 Cited Publications
製品番号: HY-123053
CAS 番号: 348086-66-8
純度:  99.91%
別名: Z-LLE-AMC
Target:  

Proteasome

研究分野:  

Neurological Disease

Z-Leu-Leu-Glu-AMC (Z-LLE-AMC) is a peptide-AMC linked substrate used to measure the postacidic-like hydrolysing activity of proteasome. Z-Leu-Leu-Glu-AMC can be used for the research of parkinson's disease .
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2
2 Cited Publications
製品番号: HY-75342
CAS 番号: 3943-74-6
Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
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2
2 Cited Publications
製品番号: HY-N3244
CAS 番号: 123702-97-6
Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects .
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2
2 Cited Publications
製品番号: HY-N0013R
CAS 番号: 3681-93-4
Vitexin (Standard) is the analytical standard of Vitexin. This product is intended for research and analytical applications. Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
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2
2 Cited Publications
製品番号: HY-120475
CAS 番号: 1232841-78-9
別名: ATH434
Target:  

α-synuclein

研究分野:  

Neurological Disease

PBT434 is a potent, orally active and cross the blood-brain barrier α-synuclein aggregation inhibitor. PBT434 can be used as a iron chelator and modulates transcellular iron trafficking. PBT434 inhibits iron-mediated redox activity and iron-mediated aggregation of α-synuclein. PBT434 prevents the loss of substantia nigra pars compacta neurons (SNpc). PBT434 has the potential for the research of Parkinson’s disease (PD) .
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2
2 Cited Publications
製品番号: HY-120475A
CAS 番号: 2387898-69-1
純度:  99.92%
別名: ATH434 mesylate
Target:  

α-synuclein

研究分野:  

Neurological Disease

PBT434 methanesulfonate is a potent, orally active and cross the blood-brain barrier α-synuclein aggregation inhibitor. PBT434 methanesulfonate can be used as a iron chelator and modulates transcellular iron trafficking. PBT434 methanesulfonate inhibits iron-mediated redox activity and iron-mediated aggregation of α-synuclein. PBT434 methanesulfonate prevents the loss of substantia nigra pars compacta neurons (SNpc). PBT434 methanesulfonate has the potential for the research of Parkinson’s disease (PD) .
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1
1 Cited Publications
製品番号: HY-N2300
CAS 番号: 62949-77-3
Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM.
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1
1 Cited Publications
製品番号: HY-N4165
CAS 番号: 6750-30-7
Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn F. .
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1
1 Cited Publications
製品番号: HY-N4290
CAS 番号: 25499-90-5
3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity .
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1
1 Cited Publications
製品番号: HY-122943
CAS 番号: 69120-07-6
Moracin D is a flavonoid that can be isolated from Morus alba. Moracin D induces cell apoptosis and shows hypoglycemic, antiadipogenic, antifungal and antitumor effects. Moracin D can be used for fungal infection and breast cancer research .
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